‘To Personalize’ or ‘Not to Personalize’: How to Balance the Need for Subject-Specific Anatomical Detail and Clinical Applicability in the Study of Musculoskeletal Loading During Movement?

The use of integrated 3D motion capture together with dynamic simulation of motion is currently an established way to study musculoskeletal loading, which today still cannot be measured non-invasively. In particular, in the field of degenerative joint disease, there is the ambition to use these techniques to contribute to patient stratification and consequent prescription of targeted rehabilitation strategies.

Likewise, their potential in defining effective treatment approaches to study gait dysfunction in children with cerebral palsy (CP) is becoming more and more accepted. In these research applications, high fidelity data from medical imaging techniques and 3D motion capture systems are abundantly used to personalize the musculoskeletal models and input data. However, when bridging into the clinical decision-making workflow, the challenges merely lie in the sparse data sets and the need to simplify the modeling workflows without losing important patient-specific features. Although not having solved this dilemma, she aims to present some of her insights and perspectives on the personalization of the simulation workflows for the study of musculoskeletal loading.

What you will learn

  • How medical imaging techniques help in personalizing musculoskeletal models
  • What it will take to make the transfer of musculoskeletal models from the lab to their clinical application
  • How to set up efficient musculoskeletal model personalization pathways


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Materialise medical device software may not be available in all markets because product availability is subject to the regulatory or medical practices in individual markets. In countries where no regulatory registration is obtained of Mimics or 3-matic Medical, a research version is available. Please contact your Materialise representative if you have questions about the availability of Materialise medical device software in your area.


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