Left Atrial Appendage Occlusion
Empowered by FEops’ predictive insights
Predicting the optimal device size and position for LAAO with standard imaging tools can be challenging, increasing the risk of complications. Leverage clinically proven AI, predictive simulations, and cloud-based collaboration to deliver safer outcomes with confidence.
Confident decisions, demonstrated outcomes
100% success with no complications in the simulation group
This clinically validated outcome is powered by advanced predictive insights and simulation technology, ensuring precise device placement, smoother interventions, and enhanced confidence in even the most complex anatomies.
2x procedural success with single device and deployment
By providing predictive insights into how devices interact with individual anatomies, optimal device placement enhances patient and clinician confidence in delivering safer, more reliable, and more efficient procedures.
+40% complete LAA closure with no leakage
Rely on precise device sizing and positioning, reducing the risk of peridevice leaks and achieving 40% more complete LAA closure with no leakage, optimizing long-term procedural efficacy.
25% less radiation and contrast medium
Achieve a 25% reduction in radiation exposure and a 26% reduction in contrast medium usage. These efficiencies are particularly valuable for patients with renal sensitivities and clinicians seeking safer working conditions.
Clinical evidence
Discover how our predictive simulations have been clinically researched, involving nearly 2,000 patients and over 260 validation cases. Here’s a glimpse into the science driving improved outcomes.
AI-enabled computer simulations enhance clinical outcomes, increase procedural efficiency, and reduce duration, contrast usage, and radiation time in LAAO procedures.
Impact of Computational Modeling on Transcatheter Left Atrial Appendage Closure Efficiency and Outcomes (2023)
AI-enabled computer simulations improve device selection and boost operator confidence, enhancing decisional impact in LAAO procedures.
Clinical Value of CT‐Based 3D Computational Modeling in Left Atrial Appendage Occlusion: An In‐Depth Analysis of the PRECISE LAAO Study (2025)
PREDICT-LAA results for US patients confirm strong device deformation correlation and significant improvements in procedural time, fluoroscopy time, and contrast usage.
Safety, Efficiency, and Accuracy of Pre-Procedural Predictive Modeling Using Artificial Intelligence Algorithm to Predict the Left Atrial Appendage Characteristics and the Appropriate Device Size for Closure (2024)
Preprocedural planning with FEops HEARTguide delivers excellent safety and efficacy for LAAC, with low peridevice leak rates (6% acute, 2% at 1-year), no device-related complications, and only 2 re-interventions.
Acute and Long Term Safety and Outcomes of Incorporating Pre‐procedural Predictive Modeling Using Artificial Intelligence Algorithm during Left Atrial Appendage Closure (2025)
Clinical data report
Clinical data showcases the impact and reliability of our technologies. Data from TAVR and LAAO procedures demonstrate improved outcomes, efficiency, and physician confidence throughout the care pathway.
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Need more information?
See how you can leverage clinically proven, AI-driven predictive simulations in your LAAO procedures in this brochure.
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Materialise Mimics and FEops’ predictive simulations are part of a continuously evolving technology platform. Some clinical evidence referenced in this content may have been generated using earlier versions of the software with capabilities that differ from the current release.
Materialise medical device software may not be available in all markets because product availability is subject to the regulatory or medical practices in individual markets. In countries where no regulatory registration is obtained of Mimics or 3-matic Medical, a research version is available. Please contact your Materialise representative if you have questions about the availability of Materialise medical device software in your area.