Using 4D CT to Understand Anatomy-Device Interaction across the Cardiac Cycle

by Julianne Spencer Principal Scientist, Medtronic

The beating heart can take a toll on a cardiac implant. When developing new or improved cardiac devices, it is important to understand this motion and how it affects implants such as heart valves. 4D Cardiac CT imaging offers unique insight into both anatomical and device geometry at multiple time points throughout the cardiac cycle.


Beyond providing just animations of cardiac motion, this data can be used in complex 3D analyses to provide quantitative answers to questions such as:

  • What anatomical geometry does an implant need to fit?
  • Which patients are appropriate candidates for a particular device?
  • How much deformation will a device undergo within the heart cycle?
  • How is the implant performing in patients?
  • Analyses on 4D CT data from live patients provides the opportunity to validate a device design while limiting expensive cadaver or animal studies.


In this webinar, Julianne Spencer from Medtronic will share how she uses the new 4D feature in the Mimics Innovation Suite 21.0 to optimize her analysis of transcatheter heart valves. She will discuss the value of 4D analysis for her work and explain how the latest version of the software is empowering her to understand device behavior, while removing hours from her previous workflow.

Julianne Spencer

About the speaker

Julianne Spencer is a Principal Scientist in the Structural Heart Research and Innovation Group at Medtronic. Her work focuses on how the anatomy interacts with transcatheter aortic valves. She previously worked in Cardiac Rhythm and Heart Failure Post Market Reliability at Medtronic. In 2013, she earned her PhD in Biomedical Engineering at the Visible Heart Lab at the University of Minnesota on the Implications and Effects of Coronary Venous Anatomy on Clinical Interventions


Materialise medical device software may not be available in all markets because product availability is subject to the regulatory and/ or medical practices in individual markets. In countries where no regulatory registration is obtained of Mimics and/or 3-matic Medical, a research version is available. Please contact your Materialise representative if you have questions about the availability of Materialise medical device software in your area.


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