Plan complex TMVR procedures consistently and accurately1
Every time.

Mimics Enlight is an innovative pre-procedural planning tool helping physicians from patient selection to intervention.

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[1] Based on accurate 3D models and consistency in taking measurements of the cardiac anatomy.

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Fast, easy clinical workflow

Mimics Enlight blends engineering know-how with clinical guidance into a fast and powerful, yet easy to use workflow. This combination enables:


Accuracy in 3D models


Consistency in critical measurements, like neo‑LVOT


Automation in report generation


Mitral Valve disease is one of the most common heart valve diseases, with nearly 1 in 10 people over the age of 75 affected by moderate to severe mitral regurgitation2.

Transcatheter mitral valve replacement (TMVR) is an emerging therapy to help this large patient population, giving a second chance to those who are too high-risk and inoperable for open-heart surgeries.

[2] Nkomo VT, Gardin JM, Skelton TN, Gottdiener JS, Scott CG, Enriquez-Sarano M. “Burden of valvular heart diseases: a population-based study.” The Lancet. 2006;368(9540):1005-1011


Based on validated, published clinical data as part of the MITRAL trial and building on the Mimics Medical technology, Mimics Enlight was developed in partnership with Henry Ford Health System.

“Successful transcatheter mitral valve replacement (TMVR) depends on [successful pre-procedural planning through] accurate sizing of the mitral annulus and avoidance of LVOT obstruction.

Dee Dee Wang MD.jpg
   Dee Dee Wang, M.D., FACC, FASE, FSCCT
Director of Structural Heart Imaging
Center for Structural Heart Disease
Henry Ford Health System

Screen your patients

Efficient patient selection for TMVR procedures is critical. Fast, consistent approaches are key. The Mimics Enlight technology affords an overview of multiple device positions at a glance. Measure, size, and assess the clinical space, including impact on critical measurements such as neo-LVOT.

  • True 3D modeling for faster measurements
  • Risk assessment of LVOT obstruction
  • Accurate quantification of anatomical structures

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Plan device selection and delivery

Plan the patient intervention in Mimics Enlight from phase selection to fluoroscopic simulation.

  • Easy device sizing and positioning
  • Visualization of complex mitral annular calcification (MAC)
  • Accurate 3D models for consistent measurements
  • Measurement of the smallest neo-LVOT

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Deliver and communicate your plans

Bring clarity to complexity by ensuring efficient planning and communication with your heart team.

  • One-click report generation
  • Easily quantify delivery pathway
  • Translate procedural plan to entire heart team

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How you can make a difference:
TMVR planning with Materialise

Do you want to experience this cutting-edge TMVR planning tool?

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Wang et al., “Three-Dimensional Printing for Planning of Structural Heart Interventions.”

Wang et al., “Multimodality Imaging of the Tricuspid Valve for Assessment and Guidance of Transcatheter Repair.”

Eng et al., “Computed Tomography for Left Atrial Appendage Occlusion Case Planning.”

Wang et al., “Validating a prediction modeling tool for left ventricular outflow tract (LVOT) obstruction after transcatheter mitral valve replacement (TMVR).”

Wang et al., “Predicting LVOT Obstruction After TMVR.”

Babaliaros et al., “Intentional Percutaneous Laceration of the Anterior Mitral Leaflet to Prevent Outflow Obstruction During Transcatheter Mitral Valve Replacement: First-in-Human Experience.”

Giannopoulos et al., “Applications of 3D printing in cardiovascular diseases.”

El Sabbagh et al., “The Various Applications of 3D Printing in Cardiovascular Diseases.”

El Sabbagh et al., “Three-dimensional prototyping for procedural simulation of transcatheter mitral valve replacement in patients with mitral annular calcification.”

Eleid et al., “Severe Mitral Annular Calcification: Multimodality Imaging for Therapeutic Strategies and Interventions.”

Vukicevic et al., “Cardiac 3D Printing and its Future Directions.”

Vukicevic et al., “3D Printed Modeling of the Mitral Valve for Catheter-Based Structural Interventions.”