Stephanie Benoit August 8, 2016

Making the world a better and healthier place was certainly the goal Materialise had in mind when they decided to donate a grant to the Centre for Rapid Prototyping and Manufacturing (CRPM) at Central University of Technology, Free State in South Africa. The grant allowed the CRPM to help some patients with life-changing interventions, and to introduce students to the benefits of using 3D printing in the medical field. One of the patients helped by the CRPM was a young woman of 32. She suffered from an ossifying fibroma tumor in her lower jaw. The surgical team decided it was necessary to immediately resect the tumor and place a custom-made laser-sintered titanium implant in the patient’s mouth.

32-year-old female patient with an ossifying fibroma tumor of the lower jaw © CRPM
32-year-old female patient with an ossifying fibroma tumor of the lower jaw © CRPM

Although the ossifying fibroma was benign and painless, these types of tumors can grow to very large proportions if left untreated. The result is a tumor filled with cementum (the calcified substance that anchors the teeth to the jawbone) which mostly occurs on the lower jawbone.

3D model of the bone and tumor © CRPM
3D model of the bone and tumor © CRPM

The team started by taking CT scans of the patient, and converting them to a 3D model in Materialise Mimics. The resulting 3D models of the bone and tumor were used as input to plan the resection planes and design the according cutting guides. After virtually going through the surgery, an implant was designed to fit the gap perfectly. The guides and models were printed in plastic and the implant itself was 3D printed in titanium.

The aim of this design was to fully cover the titanium frame and the bone around the dental implants with soft tissue. Because soft tissue does not attach itself to titanium, any exposure of the implant would lead to epithelial ingrowth around the implant. The result would be infection and eventually the loss of the implant.

Titanium implant in position No bone was used to fill the cage at this stage of the procedure to minimize the chances of infection CRPM.jpg
Titanium implant in position CRPM

The surgery was carried out successfully. By using the cutting guides, the titanium implant fit perfectly after the tumor had been resected. Just 24 hours post-surgery, the patient was already able to move her jaw normally again. Phase two of the process was recently completed. The space maintainer was removed and the cage was filled with bone harvested from the iliac crest. The third phase will see the placement of the dental implant into the augmented bone. In the final phase, a denture will be placed into the implant.

JJust 24 hours post-surgery, the patient was already able to move her jaw normally again.
Just 24 hours post-surgery, the patient was already able to move her jaw normally again.

About the CRPM:

The Centre for Rapid Prototyping and Manufacturing is part of the Central University of Technology (CUT) in South Africa. Established in 1997, the CRPM owns a range of 3D printing machines and technologies, including Plastic Laser Sintering, Direct Metal Sintering and Stereolithography printers. It is one of the best-equipped 3D printing facilities in the southern hemisphere.

The expert team at the Central University of Technology © Varsity Post
The expert team at the Central University of Technology © Varsity Post

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